Iron deficiency is a nutritional deficiency state caused primarily by inadequate iron intake, impaired absorption, or ongoing losses. It is a major driver of anaemia burden and can reduce oxygen-carrying capacity through insufficient hemoglobin synthesis.
Studies found gut microbiome changes linked to Parkinson’s risk before symptoms and hair mineral differences in diagnosed patients. Both findings need larger follow-up studies.
The European Medicines Agency has approved Shield Therapeutics' FeRACCRU® for adolescents aged 12 and older, following FDA approval of ACCRUFeR® for children 10+. The expansion was supported by Phase 3 pediatric trial data showing efficacy and safety in children as young as 1 month.
March of Dimes awarded the 2026 Richard B Johnston Jr, MD Prize to hematologist Leonard Zon for pioneering zebrafish research that illuminated blood development in embryos and led to breakthrough treatments for genetic blood disorders in children.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07546591 |
A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females |
RECRUITING | NA |
| NCT07394088 |
Assessing Clinical Impact of AI for Iron Deficiency |
NOT_YET_RECRUITING | NA |
| NCT07370688 |
Iron Infusion in Patients Undergoing Transcatheter Aortic Valve Implantation |
RECRUITING | PHASE4 |
| NCT07359599 |
The Impact of IV Iron on Exercise Capacity and Quality of Life in Pulmonary Hypertension |
RECRUITING | PHASE4 |
| NCT07277140 |
Impact of Iron Deficiency on Arrhythmic Events and Resting ECG Abnormalities in Patients Hospitalized With Heart Failure |
NOT_YET_RECRUITING | |
| NCT07217873 |
IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study |
RECRUITING | PHASE2/PHASE3 |
| NCT07084298 |
Effects of Iron Supplementation on Skeletal Muscle Properties in Females With Suboptimal Iron Storage |
NOT_YET_RECRUITING | EARLY_PHASE1 |
| NCT07081152 |
Iron Absorption and Losses in Young South African Women Living Without and With Overweight and Obesity |
RECRUITING | NA |
| NCT07078630 |
Modulation of hepcidIN With Co-supplementation of Iron and FORMulated Curcumin in Recreational Athletes |
COMPLETED | NA |
| NCT07053475 |
IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches |
RECRUITING | PHASE4 |
