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Statin Therapy In Cardiac Surgery

NCT01573143 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 1922

Last updated 2014-09-17

No results posted yet for this study

Summary

The purpose of STICS trial (Statin Therapy In Cardiac Surgery) is to test whether perioperative treatment with Rosuvastatin 20 mg once daily prevents post-operative atrial fibrillation and reduces perioperative irreversible myocardial damage in patients undergoing elective cardiac surgery.

Conditions

Interventions

DRUG

Rosuvastatin

Rosuvastatin (20 mg od) started not earlier than 8 days before surgery and continued until the 5th post-operative day included;

DRUG

Placebo

Placebo started not earlier than 8 days before surgery and continued until the 5th post-operative day included.

Sponsors & Collaborators

  • Chinese Academy of Medical Sciences, Fuwai Hospital

    collaborator OTHER

  • Chinese Academy of Medical Sciences

    collaborator OTHER

  • Peking Union Medical College

    collaborator OTHER

  • University of Oxford

    lead OTHER

Principal Investigators

  • Rory Collins, FRCP. FMed Sci · Clinical Trial Service Unit (CTSU), University of Oxford

  • Shenshou Hu, MD.PhD · Chinese Academy of Medical Sciences, Fuwai Hospital

  • Barbara Casadei, MD.DPhil.FRCP · Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford

  • Zheng Zhe, MD.PhD · Chinese Academy of Medical Sciences, Fuwai Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-09-30
Primary Completion
2014-09-30
Completion
2014-09-30

Countries

  • China

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01573143 on ClinicalTrials.gov