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Electroconvulsive Therapy (ECT) for Elderly Patients With Major Depression

NCT01559324 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 92

Last updated 2015-07-09

No results posted yet for this study

Summary

ECT (electroconvulsive therapy) is mostly given to patients between the age of 60 - 85 years. There is limited evidence on the efficacy and cognitive side-effects of right unilateral (RU) and bifrontal (BF) electrode positions, the placements that are considered safe for the elderly. As far as the investigators know no randomized controlled trials (RCTs) have yet been published describing this population treated with BF or RU ECT. Non-demented depressed patients will be randomized to either method (n = 2x36). Symptom intensity, global cognitive function and biomarkers will be related to 20 healthy comparators. Testing, evaluation of depression and blood-tests are done before ECT-treatment, after a series of 6-16 ECT and 3 months after terminated ECT-treatment.

Conditions

Interventions

DEVICE

ECT

Bifrontal ECT, low dosage

DEVICE

ECT

Right unilateral electrode position, high dosage

Sponsors & Collaborators

  • MD Tor Magne Bjølseth

    collaborator UNKNOWN

  • MD Torfinn Lødøen Gaarden

    collaborator UNKNOWN

  • Diakonhjemmet Hospital

    lead OTHER

Principal Investigators

  • Lars Tanum, Dr.Med. · University Hospital, Akershus

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2013-07-31
Completion
2013-11-30

Countries

  • Norway

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01559324 on ClinicalTrials.gov