Effectiveness of Intensive Aphasia Therapy Under Routine Clinical Conditions

Summary

The purpose of this study is to examine whether 3 weeks of intensive language therapy provided in clinical in- and outpatient settings is effective in improving everyday communication in postacute/chronic post-stroke aphasia, as measured by performance on the Amsterdam Nijmegen Everyday Language Test (ANELT).

Conditions

• Aphasia
• Stroke

Interventions

BEHAVIORAL

Intensive integrative aphasia therapy

Intensive language therapy (3 weeks, 5 days/week, \>=2 hours/day) provided in regular clinical setting and consisting of a combination of language systematic and communicative-pragmatic treatment

BEHAVIORAL

Waiting list control group

Control group starts intensive language therapy after a 3-week waiting period.

Sponsors & Collaborators

• Fresenius University of Applied Science

  collaborator OTHER

• Charite University, Berlin, Germany

  collaborator OTHER

• Entwicklungsgruppe Klinische Neuropsychologie, Klinikum Bogenhausen, München

  collaborator UNKNOWN

• Institut für Biometrie und Klinische Epidemiologie, Charité Campus Benjamin Franklin, Berlin

  collaborator UNKNOWN

• RWTH Aachen University

  collaborator OTHER

• Bundesverband für die Rehabilitation der Aphasiker e.V.

  collaborator UNKNOWN

• Universitätsklinikum Leipzig

  collaborator OTHER

• MEDIAN Klinik Grünheide

  collaborator UNKNOWN

• Brandenburgklinik Berlin-Brandenburg GmbH

  collaborator UNKNOWN

• St. Mauritius Therapieklinik

  collaborator UNKNOWN

• Aphasie- und Seniorenzentrum Josef Bergmann Vechta

  collaborator UNKNOWN

• Behandlungs- und Rehabilitationszentrum für Intensiv-Therapie Lindlar

  collaborator UNKNOWN

• Wickerklinik Bad Homburg v.d.H.

  collaborator UNKNOWN

• Asklepios Neurological Clinic Falkenstein

  collaborator OTHER

• Akademische Praxis für Sprachtherapie / Praxis für Rehabilitationswesen Aschaffenburg

  collaborator UNKNOWN

• Städtisches Klinikum München, Klinikum Bogenhausen

  collaborator UNKNOWN

• Schoen Clinic Bad Aibling

  collaborator OTHER

• m&i-Fachklinik Bad Liebenstein

  collaborator UNKNOWN

• m&i-Fachklinik Enzensberg

  collaborator UNKNOWN

• m&i-Fachklinik Herzogenaurach

  collaborator UNKNOWN

• mediclin Klinikum Soltau

  collaborator UNKNOWN

• Moritz Klinik, Bad Klosterlausnitz

  collaborator UNKNOWN

• Klinikum Christophsbad, Göppingen

  collaborator UNKNOWN

• P.A.N.-Zentrum

  collaborator OTHER

• University Hospital Muenster

  lead OTHER

Principal Investigators

• Annette Baumgaertner, PhD · Hochschule Fresenius University of Applied Science

• Caterina Breitenstein, PhD · Neurology, University of Muenster

• Agnes Floel, MD · Neurology, Universitätsmedizin Charite, CCM, Berlin

• Wolfram Ziegler, PhD · Clinical Neuropsychology Research Group (EKN), Klinikum Bogenhausen, München

• Tanja Grewe, PhD · Hochschule Fresenius University of Applied Sciences

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-04-30

Primary Completion

2015-01-31

Completion

2015-01-31

Countries

• Germany

Study Locations