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Oxycodone Versus Intravenous Morphine for Postoperative Analgesia After Hip Surgery

NCT01536301 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 246

Last updated 2025-11-19

No results posted yet for this study

Summary

The main objective is to demonstrate that postoperative analgesia by IV oxycodone (compared to morphine IV) reduces opioid-related adverse events (nausea, vomiting, pruritus, respiratory depression, urinary retention, allergies, hallucination) by 50% in adult patients operated on for prosthetic hip surgery.

Conditions

  • Arthroplasty, Replacement, Hip

Interventions

DRUG

Standard Care morphine hydrochloride

Post-operative analgesia including morphine (patient controlled analgesia).

DRUG

Oxycodone

Post-operative analgesia including oxycodone (patient controlled analgesia).

Sponsors & Collaborators

  • Centre Hospitalier Universitaire de Nīmes

    lead OTHER

Principal Investigators

  • Lana Zoric, MD · Centre Hospitalier Universitaire de Nîmes

  • Philippe Cuvillon, MD · Centre Hospitalier Universitaire de Nîmes

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-06-30
Primary Completion
2016-11-15
Completion
2016-11-15

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01536301 on ClinicalTrials.gov