Trial Outcomes & Findings for Effects of Transfusion of Older Stored Red Cells (NCT NCT01534676)

NCT ID: NCT01534676

Last Updated: 2016-10-05

Results Overview

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

3 participants

Primary outcome timeframe

2 hours after transfusion

Results posted on

2016-10-05

Participant Flow

This is a research study carried out at Columbia University Medical Center. Participants with a blood disorder and currently receive blood transfusions as treatment will be transfused fresh, stored, washed or frozen blood according to regular schedule for up to 3 years. Volunteer dedicated donors will also be asked to provide consent.

Enrolled participants (recipients) were never randomized or received transfusion on study because study closed due to poor enrollment.

Participant milestones

Participant milestones
Measure
Recipients
Participants with a blood disorder (either sickle cell disease or thalassemia) and currently receive blood transfusions as treatment - will be receiving the following transfusion according to regular schedule: a fresh blood, a stored blood, a washed blood, and a frozen blood transfusion.
Donors
Volunteer dedicated donors will be recruited to donate blood for each transfusion events over the next 3 years. Each patient with a chronic illness such as sickle cell disease or thalassemia will have one dedicated donor.
Overall Study
STARTED
2
1
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
2
1

Reasons for withdrawal

Reasons for withdrawal
Measure
Recipients
Participants with a blood disorder (either sickle cell disease or thalassemia) and currently receive blood transfusions as treatment - will be receiving the following transfusion according to regular schedule: a fresh blood, a stored blood, a washed blood, and a frozen blood transfusion.
Donors
Volunteer dedicated donors will be recruited to donate blood for each transfusion events over the next 3 years. Each patient with a chronic illness such as sickle cell disease or thalassemia will have one dedicated donor.
Overall Study
Study closed due to poor enrollment
2
1

Baseline Characteristics

Effects of Transfusion of Older Stored Red Cells

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Recipients
n=2 Participants
Participants with a blood disorder (either sickle cell disease or thalassemia) and currently receive blood transfusions as treatment - will be receiving the following transfusion according to regular schedule: a fresh blood, a stored blood, a washed blood, and a frozen blood transfusion.
Donors
n=1 Participants
Volunteer dedicated donors will be recruited to donate blood for each transfusion events over the next 3 years. Each patient with a chronic illness such as sickle cell disease or thalassemia will have one dedicated donor.
Total
n=3 Participants
Total of all reporting groups
Age, Categorical
<=18 years
2 Participants
n=99 Participants
0 Participants
n=107 Participants
2 Participants
n=206 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=99 Participants
1 Participants
n=107 Participants
1 Participants
n=206 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Sex: Female, Male
Female
0 Participants
n=99 Participants
1 Participants
n=107 Participants
1 Participants
n=206 Participants
Sex: Female, Male
Male
2 Participants
n=99 Participants
0 Participants
n=107 Participants
2 Participants
n=206 Participants
Region of Enrollment
United States
2 participants
n=99 Participants
1 participants
n=107 Participants
3 participants
n=206 Participants

PRIMARY outcome

Timeframe: 2 hours after transfusion

Population: Enrolled participants (recipients) were never randomized or received transfusion on study because study closed due to poor enrollment. No data was collected or analyzed.

Outcome measures

Outcome data not reported

Adverse Events

Recipients

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Donors

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Eldad Hod, MD

Columbia University Medical Center

Phone: 212-342-5648

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place