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Stem Cell Study of Genetics and Drug Addiction

NCT01534624 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 49

Last updated 2019-12-17

No results posted yet for this study

Summary

Background:

\- Researchers are interested in studying the roles that genes play in drug and alcohol addiction. Genes seem to account for about half of the differences between people who become addicted to drugs and people who do not. This study will collect blood and skin cell samples. These cells will be used to develop stem cells that are useful for studying how genes are related to drug use and dependence.

Objectives:

\- To study genetic and cellular differences between people who are addicted to drugs and those who are not.

Eligibility:

* Individuals between 21 and 65 years of age who do not use drugs.
* Individuals between 21 and 65 years of age who are in treatment with buprenorphine or methadone.

Design:

* Participants will be screened with a brief physical exam and medical history.
* Participants will also answer questions about physical and mental health, quality of life, and history of drug and alcohol use. A urine sample and cheek swab sample will be collected.
* Participants whose genetic samples match the study requirements will be asked to come back to provide a skin biopsy sample and a second urine sample.

Conditions

  • Induced Pluripotent Stem Cells

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    lead NIH

Principal Investigators

  • Kenzie Preston, Ph.D. · National Institute on Drug Abuse (NIDA)

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-02-07
Completion
2014-07-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01534624 on ClinicalTrials.gov