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Phenotypes and Vascular Damage in Chronic Obstructive Pulmonary Disease (COPD)

NCT01527773 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 313

Last updated 2017-08-11

No results posted yet for this study

Summary

TOPDOCS is a prospective cohort study including COPD patients from currently six study centers in Switzerland. Patients with COPD GOLD stages I-IV will be enrolled and followed-up annually for at least 3 years. Yearly assessments will include a detailed patient history, quality of life and activity questionnaires, history of exacerbations, lung function, measurements of exercise capacity, measurements of vascular function, exhaled breath analysis and blood sampling. The overall objective of the project is to establish a meticulously characterized cohort of COPD patients living in Switzerland in order to allow high quality research on the pathogenesis, treatment and complications of COPD. The specific aim of the project is to determine clinically relevant COPD phenotypes and biological factors influencing vascular function in COPD patients.

Conditions

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Malcolm Kohler, MD · University Hospital Zurich, Division of Pneumology

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-05-31
Primary Completion
2017-01-31
Completion
2017-01-31

Countries

  • Switzerland

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01527773 on ClinicalTrials.gov