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Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery

NCT01524315 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2021-02-26

No results posted yet for this study

Summary

The objective of this study is to determine whether preoperative parenteral thiamin supplementation does prevent the intra and early postoperative increase of lactate and whether this effect is related to the extent of thiamine deficiency in patients undergoing heart surgery. In addition the prevalence of major thiamin deficiency in patient undergoing heart surgery will be determined.

Conditions

Interventions

DRUG

Vitamin B1-ratiopharm

300 mg Thiaminchloridhydrochlorid, once, intravenous, preoperative

DRUG

Placebo

100 ml normal saline, intravenous, preoperative

Sponsors & Collaborators

  • Medical University of Vienna

    lead OTHER

Principal Investigators

  • Michael Hiesmayr, Prof.,MD · MU Vienna

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-02-01
Primary Completion
2015-02-01
Completion
2015-02-02

Countries

  • Austria

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01524315 on ClinicalTrials.gov