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Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness

NCT01522326 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2020-09-02

No results posted yet for this study

Summary

The objective of this study is to determine the efficacy of metoclopramide in relieving the symptoms of Acute Mountain Sickness (AMS).

It is our hypothesis that the combined antiemetic and analgesic effects of metoclopramide (which has been study-proven to be effective in relieving symptoms of migraine headache) will prove to be more efficacious in relieving symptoms of acute mountain sickness than the standard, previously-studied analgesic medication, ibuprofen.

Conditions

  • Acute Mountain Sickness
  • High Altitude Headache

Interventions

DRUG

Ibuprofen

Ibuprofen 400mg tablet. Take one dose by mouth.

DRUG

Metoclopramide

Metoclopramide 10mg tablet. Take one tablet by mouth.

Sponsors & Collaborators

  • Massachusetts General Hospital

    lead OTHER

Principal Investigators

  • Norman S Harris, MD, MFA · Massachusetts General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-03-01
Primary Completion
2017-03-01
Completion
2017-03-30

Countries

  • Nepal

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01522326 on ClinicalTrials.gov