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Population Pharmacokinetics and Metabolomics of Theophylline in Preterm Infants

NCT01509248 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 110

Last updated 2012-02-23

No results posted yet for this study

Summary

1. Population pharmacokinetics : The purpose of this study is

\- to investigate the population pharmacokinetics of theophylline in premature Korean infants and to assess the influence of demographic and clinical covariates.
2. Metabolomics : The purpose of this study are

* to predict serum theophylline levels and to assess CYP1A2 activities in premature infants by analyzing urinary metabolites of theophylline
* to examine which factors affect clearance of theophylline and CYP1A2 activity in premature infants

Conditions

  • Apea of Prematurity

Sponsors & Collaborators

  • Seoul National University Bundang Hospital

    collaborator OTHER

  • Seoul National University Boramae Hospital

    collaborator OTHER

  • Korea University Anam Hospital

    collaborator OTHER

  • Seoul National University Hospital

    lead OTHER

Eligibility

Max Age
37 Weeks
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-05-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01509248 on ClinicalTrials.gov