A Multicenter Study of the Pigmentation in the Trabecular Meshwork After Two Years of Treatment With TRAVATAN 0.004% Ophthalmic Solution
NCT01485822 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 88
Last updated 2013-05-14
Summary
The purpose of this study was to assess the pigmentation in the trabecular meshwork of patients who had been treated for at least 2 years with TRAVATAN compared with patients without exposure (or less than 1 month) to a prostaglandin analogue (PGA).
Conditions
- Open-angle Glaucoma
Interventions
- PROCEDURE
-
Trabecular Meshwork Tissue Collection
A minimum of two punches were used to remove tissue to form a sclerostomy. Tissue removed by the punch was collected for analysis. Alternatively, the tissue was collected by block excision of the meshwork with scissors at the time of sclerostomy.
- DRUG
-
Travoprost 0.004% ophthalmic solution
Sponsors & Collaborators
-
Alcon Research
lead INDUSTRY
Principal Investigators
-
Theresa Landry, PhD · Alcon Research
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-07-31
- Primary Completion
- 2012-02-29
- Completion
- 2012-02-29
More Related Trials
-
Efficacy and Safety of Travoprost 0.004% Versus Tafluprost 0.0015% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
NCT00966940 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00293761 ·Status: COMPLETED ·Phase: PHASE3
-
Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertension
NCT01253902 ·Status: COMPLETED ·Phase: PHASE4
-
A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)
NCT00051142 ·Status: COMPLETED ·Phase: PHASE3
-
Travatan Versus Timoptic in Treating Open-angle Glaucoma or Ocular Hypertension
NCT00763061 ·Status: COMPLETED ·Phase: PHASE4
-
Influence of Prostaglandins on Ocular Blood Flow in Glaucoma Patients
NCT00308945 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy Study of Travoprost APS Versus TRAVATAN
NCT00848536 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Anti-Glaucoma Medications on the Ocular Surface
NCT01315574 ·Status: TERMINATED ·Phase: PHASE4
-
A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma
NCT00051181 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprost
NCT00637130 ·Status: COMPLETED ·Phase: PHASE2
-
Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Health
NCT00761319 ·Status: COMPLETED ·Phase: PHASE3
-
Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Health
NCT00892762 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Changing to TRAVATAN® From Prior Therapy
NCT01493427 ·Status: COMPLETED ·Phase: PHASE4
-
Investigation of Intraocular Pressure (IOP) Reduction Efficacy of Travoprost Ophthalmic Solution in Patients With Normal Tension Glaucoma
NCT01995136 ·Status: COMPLETED ·Phase: PHASE4
-
Travoprost 0.004% Versus Pilocarpine 1% in Patients With Chronic Angle Closure Glaucoma (CACG)
NCT00762645 ·Status: COMPLETED ·Phase: PHASE4
-
Assessment of Intraocular Pressure (IOP) Control in Subjects With Open-Angle Glaucoma or Ocular Hypertension Treated With Travoprost 0.004% (TRAVATAN® Z) or Bimatoprost 0.01% (LUMIGAN®)
NCT01464424 ·Status: COMPLETED ·Phase: PHASE4
-
Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertension
NCT00670033 ·Status: COMPLETED ·Phase: PHASE2
-
IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertension
NCT00527501 ·Status: COMPLETED ·Phase: PHASE2
-
Divided Dose of TRAVATAN®
NCT01298687 ·Status: COMPLETED ·Phase: PHASE2
-
Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN
NCT00798759 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00293787 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Changing to TRAVATAN® From Prior Therapy
NCT01510145 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Travatan Z and Xalatan on Ocular Surface Health
NCT00708422 ·Status: COMPLETED ·Phase: PHASE4
-
Azopt (Brinzolamide 1.0%) Plus Travatan (Travoprost 0.004%) in Treating Patients With Chronic Angle-Closure Glaucoma (CACG)
NCT00758342 ·Status: TERMINATED ·Phase: PHASE4
-
Travoprost Five Day Posology Study
NCT01114893 ·Status: COMPLETED ·Phase: PHASE2