Prevalence and Long-term Impact of Non-atherosclerotic CAD

NCT01479140 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 160

Last updated 2021-01-15

No results posted yet for this study

Summary

Despite a relatively high prevalence of non-atherosclerotic coronary artery disease (NACAD) among young women, the majority of these abnormalities were misdiagnosed in this population, and thus treatments were not targeted adequately in this patient population. Furthermore, the short and long-term cardiovascular outcomes of young women with NACAD have not been evaluated. Given the importance of NACAD in young women, the challenges of diagnosis and subsequent treatment, and unknown outcomes with NACAD, we propose a prospective registry to further evaluate this population. We propose to evaluate young women (age \< or equal to 55) presenting with myocardial infarction (MI) prospectively, to diagnose the etiology of MI differentiating atherosclerotic versus NACAD, to correlate the prevalence of FMD in other vascular territory, and to evaluate the long-term outcome of young women with NACAD in comparison to those with atherosclerotic CAD over a 5-year follow-up.

Conditions

Sponsors & Collaborators

  • University of British Columbia

    collaborator OTHER
  • Cardiology Research UBC

    lead OTHER

Principal Investigators

  • Jacqueline Saw, MD · University of British Columbia

Eligibility

Min Age
19 Years
Max Age
55 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-12-31
Primary Completion
2021-01-13
Completion
2021-01-13

Countries

  • Canada

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01479140 on ClinicalTrials.gov