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The Hurria Older PatiEnts (HOPE) With Breast Cancer Study

NCT01472094 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 700

Last updated 2025-11-10

No results posted yet for this study

Summary

The goal of this study is to develop a "bedside to bench" model of clinical and biological predictors for toxicity to adjuvant and neoadjuvant chemotherapy in older adults with breast cancer. The investigators will develop a predictive model using clinical and biological predictors of toxicity to adjuvant and neoadjuvant chemotherapy in older adults with breast cancer. The investigators will also determine the association between clinical and biological factors and reduced relative dose intensity of the prescribed chemotherapy regimen. In addition, the investigators will explore specific chemotherapy toxicities associated with reduced relative dose intensity of a prescribed regimen.

Conditions

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • National Institute on Aging (NIA)

    collaborator NIH

  • City of Hope Medical Center

    lead OTHER

Principal Investigators

  • Mina Sedrak, MD · City of Hope Medical Center

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-09-09
Primary Completion
2018-12-02
Completion
2026-09-18

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01472094 on ClinicalTrials.gov