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Effect of Carum Carvi on Thyroid Hormones and TSH Level

NCT01471288 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2011-11-15

No results posted yet for this study

Summary

Carum Carvi has been frequently used in traditional medicine for a variety of disease ranging from dyspepsia to Alzheimer's disease.We observed high TSH levels in few patients with thyroid cancer who receiving Carum Carvi despite being on suppressive dose of levothyroxin. TSH level returned to normal after discontinuation of the Carum carvi. This observation led to a pilot study for evaluation of the effect of carum carvi on thyroid function.

Conditions

  • Thyroid Cancer Patients

Interventions

DRUG

Carum Cravi

40mg/kg of body weight

DRUG

Placebo

Placebo

Sponsors & Collaborators

  • Pharmaceutical Research Center

    collaborator UNKNOWN

  • Mashhad University of Medical Sciences

    lead OTHER

Principal Investigators

  • Seyed Rasoul Zakavi, MD. IBNM · Nuclear Medicine Research Center

  • Mohammad Ramezani, Ph.D., Pharm.D · Pharmaceutical Research Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-05-31
Primary Completion
2011-12-31

Countries

  • Iran

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01471288 on ClinicalTrials.gov