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Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers

NCT01461174 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2015-02-04

No results posted yet for this study

Summary

The aim of this study is to assess the utility of sleep deprivation as a potential model for prediction of clinical efficacy using a combination of cognitive physiological endpoints.

Conditions

  • Healthy

Interventions

DRUG

Modafinil

200 mg tablet, single dose

DRUG

Donepezil

Donepezil or placebo, 5 mg tablet one per day, 15 days

DRUG

Memantine

Memantine or placebo, 10 mg tablet one per day, 15 days

Sponsors & Collaborators

Principal Investigators

  • Christine Audebert · CIC CPCET

Study Design

Allocation
RANDOMIZED
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2014-11-30
Completion
2014-11-30

Countries

  • France

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01461174 on ClinicalTrials.gov