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VH-IVUS Plaque Composition Analysis By Fractional Flow Reserve

NCT01444599 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2015-03-24

No results posted yet for this study

Summary

Recent clinical trials demonstrated that virtual histology-intravascular ultrasound (VH-IVUS) is a useful test predicting clinical outcomes of the coronary artery disease (CAD). Thin cap fibroatheroma (VH-TCFA) was proposed a predictor of cardiovascular event by VH-IVUS combined with more than 70% plaque burden and less than 4mm² minimal lumen area (MLA) by IVUS. Fractional flow reserve (FFR) is an established index of the physiological significance of a coronary stenosis. Recent large scale trials demonstrated FFR guided PCI showed favorable clinical outcomes. VH-IVUS represents anatomical severity, but FFR represents functional severity of CAD. Few studies reported relevance between two tests. Aim of this study was to investigate whether the geometry and composition of lesions were different under FFR criteria.

Conditions

  • Coronary Disease

Sponsors & Collaborators

  • Seoul National University Hospital

    collaborator OTHER

  • Inje University

    lead OTHER

Principal Investigators

  • Joon Hyung Doh, MDPhD · Inje University Ilsan Paik Hospital

Eligibility

Min Age
20 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-03-31
Primary Completion
2014-08-31
Completion
2014-12-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01444599 on ClinicalTrials.gov