MedTrace Logo

Intervention With Selenium and Q10 on Cardiovascular Mortality and Cardiac Function in the Elderly Population in Sweden

NCT01443780 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 443

Last updated 2011-10-03

No results posted yet for this study

Summary

The dietary supplements selenium and Q10 has been evaluated in a double blind placebo-controlled study in an elderly Swedish population. The hypothesis is that as a majority of Northern Europeans suffers insufficient levels of selenium that is used by the cell in the building of at least 25 different enzyme systems in the body, and that the cell need presence of Q10 in order to produce the selenium containing enzymes, we wanted to evaluate the effect of a combined intervention of the two supplements in an elderly population in Sweden. All participants were controlled every 6 months, and the intervention was 48 months in each participant. Besides blood samples, echocardiography and cardiac natriuretic peptides were analyzed at start, every 6 months and at end of the study.

Conditions

  • Cardiovascular Mortality
  • Cardiac Function

Interventions

DIETARY_SUPPLEMENT

Selenium and ubiquinon (Q10) combined

A combination of 200 mg/day of coenzyme Q10 (Bio-Quinon 100 mg B.I.D, Pharma Nord, Vejle, Denmark) and 200 µg/day of organic selenium (SelenoPrecise 200 µg, Pharma Nord), or placebo

Sponsors & Collaborators

  • Ostergotland County Council, Sweden

    collaborator OTHER

  • The Swedish Research Council

    collaborator OTHER_GOV

  • Pharma Nord

    collaborator INDUSTRY

  • University Hospital, Linkoeping

    lead OTHER

Principal Investigators

  • Urban Alehagen, PhD, MD · Inst of Medicine and Health, University Hospital of Linköping, Sweden

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
70 Years
Max Age
87 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2003-01-31
Primary Completion
2010-02-28
Completion
2010-02-28

Countries

  • Sweden

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01443780 on ClinicalTrials.gov