Identification the Cause of Silent Cerebral infarctiON in Healthy Subjects (ICONS)
NCT01429948 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 581
Last updated 2011-09-07
Summary
We hypothesized that paradoxical embolism may be one of the main mechanisms of silent cerebral infarction (SCI) located outside the perforating artery territory. In the present study, we evaluated the association between SCI and paradoxical embolism detected by agitated saline transcranial Doppler (TCD) monitoring in healthy subjects without history of stroke or transient ischemic attack (TIA). We also compared the frequency and amount of paradoxical embolism between healthy subjects with SCI and acute stroke patients with presumed cryptogenic embolism or conventional stroke mechanisms.
Conditions
- Cerebral Infarction
Sponsors & Collaborators
-
Samsung Medical Center
lead OTHER
Principal Investigators
-
Oh Young Bang, MD, PhD · Samsung Medical Center, Sungkyunkwan University
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-04-30
- Primary Completion
- 2011-01-31
- Completion
- 2011-05-31
Countries
- South Korea
Study Locations
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