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Study of the Aerosol Deposition With Vented and Unvented Jet Nebulizer in Healthy Subjets

NCT01428323 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 7

Last updated 2011-09-02

No results posted yet for this study

Summary

Open-vent jet nebulizers are frequently used to promote drug lung deposition but their clinical efficacy and indications are not clear.

Our study aimed to compare inhaled mass, and lung deposition of amikacin by using a jet nebulizer (Sidestream) under two different configurations: vented and unvented coupled to a 110 ml corrugated piece of tubing.

Conditions

  • Aerosol Drug Therapy

Interventions

DEVICE

Vented and Unvented Jet Nebulizer

Nebulizers used with 500mg aminoglycosides in 4ml until One minute after the sputerring point.

Sponsors & Collaborators

  • Fonds National de la Recherche Scientifique

    collaborator OTHER

  • Cliniques universitaires Saint-Luc- Université Catholique de Louvain

    lead OTHER

Study Design

Allocation
RANDOMIZED
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-01-31
Primary Completion
2011-09-30
Completion
2011-09-30

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01428323 on ClinicalTrials.gov