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Pregabalin and Remifentanil - Analgesia and Ventilation

NCT01419405 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2014-09-12

No results posted yet for this study

Summary

In this experimental study on healthy volunteers we explored the effect of pregabalin alone and in combination with remifentanil on acute experimental pain and ventilatory function.

Conditions

Interventions

DRUG

Pregabalin

hard capsule, 150 mg, 2 times, 2 days

DRUG

Remifentanil

50-90 min: TCI 0.6 ng/mL, 100-140 min: 1.2 ng/mL, 150-190 min: TCI 2.4 ng/mL

DRUG

sugar pill, saline infusion

hard capsule, 150 mg, 2 times, 2 days, saline infusion

Sponsors & Collaborators

  • Oslo University Hospital

    lead OTHER

Principal Investigators

  • Audun Stubhaug, MD, DMedSci, Prof. · Oslo University Hospital HF, Division of Critical Care

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-12-31
Primary Completion
2012-03-31
Completion
2012-03-31

Countries

  • Norway

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01419405 on ClinicalTrials.gov