Measurement and Comparison of the Occlusive and Hydrating Capacity of Three Silicone Gels and One Gel Cream

Summary

Study hypothesis: Is Alhydran gel-cream as efficient as silicone gel for skin occlusion and hydration?

For this study 16 volunteers and ten patients with healed full thickness burns will be included.

After a short period of acclimatization four test areas will be determined. For healthy volunteers the standard zones are located on the inner forearm, two on each forearm.

For patients with healed burns the 4 test zones are located on either the healed donor site or the healed skin grafted area.

In each test zone baseline measurements will be taken before application of the products.After application of the three silicone gels and the hydrating gel cream the trans epidermal water loss (TEWL) and the moisture content of the stratum corneum will be measured by using the TEWAmeter®TM300 and the Corneometer® CM825 (Courage \& Khazaka).

Conditions

• Scar Tissue or Healthy Skin

Interventions

DRUG

Dermatix

1 application of Dermatix

DRUG

Kelocote

1 application of Kelocote

DRUG

BAP scar gel

1 application of BAP scar gel

DRUG

Alhydran

1 application of Alhydran

DRUG

Bap Scar Care T

1 application of BAP Scar Care T

DRUG

Bap Scar Care S

1 Application of Bap Scar Care S

DRUG

Mepiform

1 application of Mepiform

DRUG

Scar Ban Elastic

1 application of Scar Ban Elastic

Sponsors & Collaborators

• University Hospital, Ghent

  lead OTHER

Principal Investigators

• S. Monstrey, MD PhD · University Hospital, Ghent

Study Design

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2011-06-30

Primary Completion

2012-07-31

Completion

2012-07-31

Countries

• Belgium

Study Locations