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Somatic Stem Cells in Endometriosis

NCT01412138 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2015-04-22

No results posted yet for this study

Summary

Human endometrium is a very dynamic tissue characterized by cyclical process of proliferation, differentiation and cellular shedding as part of each menstrual cycle. This issue suggests the presence of somatic stem cells. Endometriosis is characterized by presence of endometrium outside the uterine cavity. The existence of a somatic stem cell population in endometrium could explain the incorrect proliferation of these cells, which would lead to formation of endometriotic foci.

Conditions

  • Endometriosis

Interventions

OTHER

genetic analysis

1. To identify by flow cytometry through technique of "Side Population" the population of somatic stem cells present in both human endometrial eutopic and ectopic endometrium of women with ovarian endometriosis, peritoneal and recto-vaginal. 2. In vitro culture conditions for cell proliferation. 3. To characterize the somatic stem cell population using techniques of endometriotic cell and molecular biology. 4. Compare the results obtained from patients with endometriosis with control patients (without endometriosis) earlier work by our group.

Sponsors & Collaborators

  • Igenomix

    lead INDUSTRY

Principal Investigators

  • Carlos Simon, MDPhd · IVI Valencia

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2016-04-30
Completion
2016-04-30

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01412138 on ClinicalTrials.gov