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Cancer Driving Mutations in Endometriosis Lesions and Development of Progesterone Resistance

NCT03756480 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 135

Last updated 2025-06-26

No results posted yet for this study

Summary

This study will test the hypothesis that the molecular changes present in ectopic endometriosis lesions correlate with progesterone-resistant disease (using the criteria defined in this study) and are present in matched eutopic endometrium.

Conditions

  • Endometriosis
  • Endometrial Diseases

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • Johns Hopkins University

    lead OTHER

Principal Investigators

  • James Segars, MD, FACOG · Professor

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-01
Primary Completion
2024-10-01
Completion
2026-10-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03756480 on ClinicalTrials.gov