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Disturbance of Water and Sodium Metabolism After Surgery of Sellar Lesions, and Correspond Clinical Strategy

NCT01406041 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 350

Last updated 2020-03-19

No results posted yet for this study

Summary

The fluid and electrolyte imbalance (FEI) is pretty common encountered during the clinical process of patients suffered sellar lesions. Moreover, if the patients are undergone the surgery for remove the lesion, FEI happens in all cases without exception. Hypo- and hyper-natremia is the most common electrolyte disorder, which is directly correlated to the patients' outcome. However, in clinical works, different sellar diseases cause variant features of FEI. For example, after the surgery of craniopharyngioma, the hyponatremia and hypernatremia always happen alternatively even without any precursor manifestation. Under this situation, it is quite difficult for fluid supplement. In contrast, the severe FEI will cause poor outcome, even death. So it is necessary to systematically collect and review the clinical data of sellar lesions. Through the analysis of variant FEI patterns of sellar diseases, more precise strategy for clinical fluid replacement will be proposed.

Conditions

  • The Patients Suffered With Sellar Diseases
  • The Fluid and Electrolyte Imbalance Happened After Surgery

Interventions

BIOLOGICAL

Chemical and physical detection

CVP, Urine volume per day, Blood electrolytes, Urine sodium per day, Pituitrin

Sponsors & Collaborators

  • Southern Medical University, China

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2020-01-30
Completion
2021-05-12

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01406041 on ClinicalTrials.gov