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Algorithm-Guided Transfusions in Cardiac Surgery Patients for Reduction of Drainage Blood Losses

NCT01402739 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2015-06-15

No results posted yet for this study

Summary

Cardiac surgery patients have a risk to need allogeneic blood transfusions that depends on several risk factors, e.g. the type of surgery, concomitant medication with anticoagulants, and postoperative chest tube output. Allogeneic blood transfusion is associated with transfusion reactions, infection transmission, and postoperative morbidity and mortality. The aim of this study is to investigate, whether cardiac surgery patients have a reduced postoperative chest tube output and transfusion need when using a point-of-care guided transfusion algorithm compared to standard of care transfusion protocols.

Conditions

  • Chest Tube Output
  • Allogeneic Blood Transfusions

Interventions

OTHER

Point of Care Coagulation Monitoring Guided Transfusion Algorithm

(thromboelastometry, aggregometry, blood gas analysis)

OTHER

standard coagulation monitoring guided transfusion algorithm

aPTT, ACT, platelet count, hemoglobin, fibrinogen

Sponsors & Collaborators

  • Michael Sander

    lead OTHER

Principal Investigators

  • Michael Sander, MD · Dept. of Anesthesiology CCM/CVK Charité Universitätsmedizin Berlin

  • Claudia D Spies, MD · Dept. of Anesthesiology CCM/CVK Charité Universitätsmedizin Berlin

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-08-31
Primary Completion
2015-06-30
Completion
2015-06-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01402739 on ClinicalTrials.gov