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Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC)

NCT01392092 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 16

Last updated 2018-04-05

No results posted yet for this study

Summary

N-acetylcysteine (NAC) is a medication that the Food and Drug Administration (FDA) has approved for several medical uses, such as dissolving mucus in patients with breathing problems, treating overdose from acetaminophen (Tylenol), and protecting the kidneys from toxic substances.

Some recent studies suggest that NAC could be useful in the treatment of other disorders including addictions. One purpose of this study is to determine whether NAC alters the level of brain glutamate (a chemical that excites brain cells). The other main purpose is to determine whether NAC affects how much cocaine people use.

Conditions

  • Cocaine Abuse or Dependence
  • Cocaine Related Disorders

Sponsors & Collaborators

  • Wayne State University

    lead OTHER

Principal Investigators

  • Mark Greenwald, PhD · Wayne State University

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-07-31
Primary Completion
2017-06-30
Completion
2017-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01392092 on ClinicalTrials.gov