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Hepatic Sugar Metabolism Measured by PET/CT in Patients and Healthy Subjects

NCT01369979 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 13

Last updated 2012-06-26

No results posted yet for this study

Summary

The investigators wish to determine the lumped constant (LC), which is a correction factor necessary for converting measurements of hepatic FDG metabolism (measured by PET) to those of regular glucose in patients with cirrhosis and healthy subjects.

Working hypothesis

* LC for FDG in liver tissue is not significantly different from unity in healthy subjects
* LC for FDG in liver disease is significantly different from LC in healthy liver
* Insulin changes the LC for FDG in liver tissue, but not by the same factor in liver disease and healthy subjects.

Conditions

Interventions

PROCEDURE

Liver vein catheter

Liver vein catheter is placed in the heptic vein via the femoral vein, using fluoroscpoy as guidance.

Sponsors & Collaborators

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Michael Sørensen, MD PhD · Aarhus University Hospital, PET-centre

Eligibility

Min Age
40 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-05-31
Primary Completion
2012-06-30
Completion
2012-06-30

Countries

  • Denmark

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01369979 on ClinicalTrials.gov