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Cognitive Dysfunction in Postural Tachycardia Syndrome

NCT01366963 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2016-08-17

No results posted yet for this study

Summary

A common complaint among people with Postural Tachycardia Syndrome (POTS) is "brain fog" or difficulty concentrating. This is very poorly understood. To better understand this cognitive dysfunction, the investigators will test people with POTS and people without POTS using various neuropsychiatric instruments. The investigators hypothesis is that people with POTS will have greater abnormalities on neuropsychiatric testing than normal controls.

Conditions

  • Postural Tachycardia Syndrome

Interventions

BEHAVIORAL

Seated Measurements

The following measurements will take place in a seated position: Ruff 1 \& 7 (visual search and attention processes) Trails A \& B (Tests of scanning, mental flexibility and executive processes) Symbol Digit Modalities Test (SDMT)(attention and psychomotor speed) Stroop Test (naming response to certain stimuli) Verbal Fluency (COWA) Randt Wechsler Test of Adult Reading (WTAR)

BEHAVIORAL

Standing Measurements

The following will be measured in a standing position (at least 5 minutes) Orthostatic Vital Signs Randt Paired Words Subtest Digits Forward and Backward Alternate COWA test

BEHAVIORAL

Self-Administered Surveys

Center for Epidemiologic Studies Depression Scale (CES-D) Cognitive-Somatic Anxiety Questionnaire (CSAQ) Subjective Neurocognitive Inventory (SNI)

Sponsors & Collaborators

  • Vanderbilt University

    lead OTHER

Principal Investigators

  • Satish Raj, MD, MSCI · Vanderbilt University

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2015-06-30
Completion
2015-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01366963 on ClinicalTrials.gov