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Role of Active Valvular Calcification and Inflammation in Patients With Aortic Stenosis

NCT01358513 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 121

Last updated 2018-06-25

No results posted yet for this study

Summary

The aortic valve is the main outlet valve from the heart. This valve can become diseased and narrowed when it needs to be replaced with an artificial valve. Currently, this is the commonest reason for someone to undergo a heart valve operation in the UK. Unfortunately, there are no medical treatments that can prevent or delay the progression of this disease process. Here, the investigators propose to use new state-of-the-art imaging techniques to better understand the disease process so that the investigators can effectively design and assess potential new treatments. The ultimate aim is to stop this disease before patients need to have surgery. In addition the investigators believe this technique will allow us to predict the rate of progression of the disease

Conditions

  • Aortic Stenosis

Sponsors & Collaborators

  • NHS Lothian

    collaborator OTHER_GOV

  • British Heart Foundation

    collaborator OTHER

  • University of Edinburgh

    lead OTHER

Eligibility

Min Age
50 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-07-31
Primary Completion
2014-07-31
Completion
2015-07-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01358513 on ClinicalTrials.gov