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Vascular Alteration and Evolution of Cognitive Impairment

NCT01351961 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 131

Last updated 2025-09-15

No results posted yet for this study

Summary

In the cross sectional study "Adelahyde 1" which took place between 2001 and 2005, the investigators data suggest that vascular alterations may play a role in the setting of subjective memory complaints.

This longitudinal study (Adelahyde 2) aims to confirm the role of vascular factors in the evolution of cognitive function and dementia.

Conditions

Interventions

BIOLOGICAL

blood sampling

take a sample of blood, 46 ml

PROCEDURE

brain MRI and TEP cerebral

magnetic resonance imaging

OTHER

Assessment of cognitive functions

Folstein MMSE, Mac Nair scale, Depression (GDS) scale, The Benton Visual Retention Test, Test of verbal fluency, formal and categorical, Trail Making Test, Grober et Buschke scale (RL/RI-16), Apathy Robert scale, Praxis rating Scale .

OTHER

Electrocardiogram and blood pressure

Electrocardiogramm Blood pressure monitoring

PROCEDURE

Vascular explorations

Pulse wave velocity, VWF, IMT

BIOLOGICAL

Urine sample

Sponsors & Collaborators

  • Central Hospital, Nancy, France

    lead OTHER

Principal Investigators

  • Athanase BENETOS, professor · CHU NANCY

Study Design

Allocation
NA
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
65 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-04-30
Primary Completion
2013-11-30
Completion
2013-11-30

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01351961 on ClinicalTrials.gov