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Ethanol Lock for Prevention of Central Line-Associated Blood Stream Infections

NCT01344590 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2011-04-29

No results posted yet for this study

Summary

Vascular access via central venous lines (CVL) is essential to the care of many patients in the intensive care setting. While the value of these lines for the management of critically ill patients is generally accepted, the potential for line-associated blood stream infection is a known complication of the use of this intervention.

Ethanol is an effective antimicrobial agent with activity against a broad spectrum of human pathogens.

The purpose of this study is to evaluate the effectiveness of daily treatment of the catheter lumen with ethanol to prevent central line associated blood stream infections (CLABSI). The hypothesis is that this treatment will reduce the incidence of CLABSI compared to maintenance of the lines with normal saline alone.

Conditions

  • Central Lines in ICU Patients

Interventions

OTHER

Normal Saline

Standard saline procedure will be utilized.

OTHER

Ethanol 70% pharmaceutical grade

70% pharmaceutical grade ethanol will be instilled in the line in a volume calculated to fill the lumen and the hub.

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Ron Turner, MD · University of Virginia

Study Design

Allocation
RANDOMIZED
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2012-05-31
Completion
2012-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01344590 on ClinicalTrials.gov