Study of Pazopanib and Vorinostat in Patients With Advanced Malignancies
NCT01339871 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 152
Last updated 2017-06-16
Summary
The goal of this clinical research study is to find the highest tolerable dose of the combination of pazopanib and vorinostat that can be given to patients with advanced cancer. The safety of the drug combination will also be studied.
Conditions
Interventions
- DRUG
-
Pazopanib
Starting dose 400 mg orally daily of 28 day cycle.
- DRUG
-
Vorinostat
Starting dose 100 mg orally daily of 28 day cycle.
Sponsors & Collaborators
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Siqing Fu, MD,PHD · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-04-20
- Primary Completion
- 2017-06-07
- Completion
- 2017-06-07
- FDA Drug
- Yes
Countries
- United States
Study Locations
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