Post-stroke Cognitive Impairment and Dementia

Summary

Projections from epidemiological studies suggest that, among the Western adult population, one in three will present a cerebrovascular accident (stroke), severe cognitive disorders, or both. To better diagnose the Vascular Cognitive Impairment, new standards were developed by a North America working group which are under validation. It is essential to adapt these standard for French-speaking population, and especially to define cutoff scores of the cognitive battery to determine cognitive deficit.

The investigators propose a study coordinated by the University-Hospital of Amiens for french speaking centers. This study will investigate this battery with 906 controls to define the standards and 302 stroke affected patients to define the frequency and cognitive mechanisms. This step is essential for people to benefit from these new standards.

Conditions

• Stroke
• Cognitive Disorders
• Behavioral Disorders

Interventions

BEHAVIORAL

French adaptation of NINDS-Canadian Stroke Network battery

* clinical: post-stroke neurological follow-up assessment * neuropsychological: comprising the NINDS-Canadian Stroke Network neuropsychological battery * MRI

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens

  lead OTHER

Principal Investigators

• Olivier Godefroy, PhD-MD · CHU Amiens

• Hilde Henon, MD · CHRU LILLE

• Hervé Taillia, PhD-MD · HIA val de grace

• Serge Timsit, PhD-MD · CHU Brest

• Claudine Nedelec, MD · CH La Rochelle

• catherine thomas, MD · CHU SAINT-ETIENNE

• Maurice Giroud, PhD-MD · CHU Dijon

Study Design

Allocation

NA

Purpose

DIAGNOSTIC

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

40 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2010-08-31

Primary Completion

2016-12-31

Completion

2016-12-31

Countries

• France

Study Locations