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The Impact of Fitness on Vascular Dysfunction in Adolescents With Type 1 Diabetes

NCT01337947 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 32

Last updated 2014-09-29

No results posted yet for this study

Summary

The principal hypothesis of this study is that the micro and macro vasculature of young diabetes mellitus type 1 (DM1) patients is particularly susceptible to atherogenic factors which cause vascular dysfunction at multiple levels of the arterial vasculature and that this dysfunction is demonstrable using state-of-the-art ultrasound methods. The investigators further hypothesize that interventions, such as exercise, that are readily integrated into the daily life of individuals with DM1 can mitigate or reverse these early vascular changes and thereby diminish the otherwise predictable longer-term development of cardiovascular disease (CVD) in type 1 DM

Conditions

Interventions

DRUG

Definity microbubbles

Definity microbubbles are used as a contrast agent to image blood flow in skeletal muscle

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Eugene Barrett, MD · University of Virginia

Eligibility

Min Age
12 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-04-30
Primary Completion
2013-11-30
Completion
2013-11-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01337947 on ClinicalTrials.gov