Modified Video-assisted Thoracoscopic Surgery (VATS) Lobectomy for Early-stage Non-small Cell Lung Cancer (NSCLC)

Summary

The purpose of this study is to modify the surgical technique of VATS (video-assisted thoracoscopic surgery) lobectomy for early-stage non-small cell lung cancer.

Conditions

• Lung Cancer

Interventions

DEVICE

VATS lobectomy using modified equipments

the procedure of this group is the same with standard VATS lobectomy group.the VATS surgical equipments used in the group are designed according to the experience of chinese lobectomy surgery. All the patent applications of the surgical equipments are granted. proprietor of the patents is Jun Wang, head of Department of Thoracic surgery of people's hospital, peking university. Details of the modified equipments: Lobectomy Equipments Pack (Manufacturer B.J.ZH.F.Panther Medical Equipment Co.,Ltd.) consists of 8 basic surgical equipments, which are crafoord dissecting and ligature forcep, Yankauer suction tube, mixter dissecting and ligature forceps(long),mixter dissecting and ligature forceps(short), atraumatic-grip aorta-aneurysma clamp with toothing De Bakey, De Bakey atraumatic-grip vascular forcep, Bozemann tite grip needle holder, Winter placenta and ovum forcep.

PROCEDURE

VATS lobectomy using less staples

VATS lobectomy with at most 4 staples used, aimed at reduced hospital cost.This procedure is similar with the standard VATS lobectomy procedure without staples limits. The lobar vessels and bronchus are stapled. However, the interlobar fissures should be deal with electronic cautery, harmonic scalpel,or suturing.

PROCEDURE

Standard VATS lobectomy

VATS lobectomy without new equipments and limitation of staples, same with the current procedure of VATS lobectomy performed in thoracic departments of Peking university people's hospital and the Collaborators. All procedures were conducted under general anesthesia with double lumen intubation. The thoracoscope was introduced through 7th or 8th intercostals space on the mid-axillaries line. The 4 cm long utility incision was made on the 4th or 5th intercostals space anterior axillary's line without rib-spreading. A third retraction incision located on the 7th or 8th intercostals space sub-scapular line. The surgeon stands on the ventral side of patient using an electrocautery hook and a suction device through the utility incision. Anatomic lobectomy was performed with systemic mediastinal lymph node dissection for lung cancer patients.

PROCEDURE

Open lobectomy

standard lobectomy procedure by thoracotomy approach

Sponsors & Collaborators

• Shanghai Zhongshan Hospital

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Sun Yat-sen University

  collaborator OTHER

• The First Hospital of Jilin University

  collaborator OTHER

• Central South University

  collaborator OTHER

• Jiangsu Cancer Institute & Hospital

  collaborator OTHER

• Beijing Friendship Hospital

  collaborator OTHER

• Xuanwu Hospital, Beijing

  collaborator OTHER

• Peking University

  collaborator OTHER

• Fujian Provincial Hospital

  collaborator OTHER

• Fuzhou General Hospital

  collaborator OTHER

• Beijing Haidian Hospital

  collaborator OTHER

• Fuzhou Pulmonary Hospital of Fujian

  collaborator OTHER

• Peking University People's Hospital

  lead OTHER

Principal Investigators

• Jun Wang, MD · Department of Thoracic Surgery, Center for Mini-invasive Thoracic Surgery, People's Hospital, Peking University

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-04-30

Primary Completion

2016-12-31

Completion

2016-12-31

Countries

• China

Study Locations