Characterisation of T Lymphocytes, NK Cells and Macrophages in Melanoma Patients
NCT01336270 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 217
Last updated 2026-03-06
Summary
Melanoma tumor tissue ( in particular regressive areas) present a lymphocytic infiltrate with an anti-tumoral specificity. The aim of the study is to analyse at different stages of the disease, tumor samples and to characterise the cellular infiltrate in situ ( in particular T lymphocytes, NK cells and macrophages), the role of inhibitor receptors on in situ immunosuppression, and potential modulation by medical treatments such as dacarbazine.
Conditions
Interventions
- OTHER
-
biological collection
to collect some human cell samples in melanoma
Sponsors & Collaborators
-
URC-CIC Paris Descartes Necker Cochin
collaborator OTHER -
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Marie Françoise Avril, MD, PhD · Assistance Publique - Hôpitaux de Paris
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-05-31
- Primary Completion
- 2013-11-30
- Completion
- 2014-03-31
Countries
- France
Study Locations
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