Elderly Cancer PatIents, Safety and qualiTy of Life Under immunOtheraPies
NCT03673332 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2026-01-22
Summary
The co-primary objectives will be to assess the safety and quality of life under treatment.
Conditions
- Advanced or Metastatic Melanoma
- Advanced or Metastatic NSCLC
Interventions
- DRUG
-
immune-checkpoint inhibitors therapies
All patients included in this study will receive approved immune-checkpoint inhibitors therapies, such as CTLA-4, PD-1, and PD-L1 inhibitors.
Sponsors & Collaborators
-
Société Francophone d'Onco-Gériatrie
collaborator OTHER -
Institut Paoli-Calmettes
lead OTHER
Principal Investigators
-
Renaud Sabatier, MD · Institut Paoli-Calmettes
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-10-16
- Primary Completion
- 2024-10-29
- Completion
- 2024-10-29
Countries
- France
Study Locations
More Related Trials
-
Targeted Radionuclide Therapy for Metastatic Melanoma [131I] ICF01012
NCT03784625 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Quality of Life and Physical Fitness After Immune Checkpoint Inhibitors
NCT03946007 ·Status: COMPLETED
-
Ipilimumab With Carboplatin and Paclitaxel in Patients With Unresectable Stage III and Stage IV Melanoma
NCT01676649 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Tolerance of Targeted Therapy Used in Metastatic Melanoma in Patients Aged Over 65 and 75-year-old
NCT03155217 ·Status: COMPLETED
-
Immuno-monitoring of Patients With Metastatic Melanoma (AJCC Stadium IV) Under Chemotherapy
NCT02332642 ·Status: COMPLETED
-
Evaluation of Safety and Efficacy of Patients With Four and More Symptomatic Brain Metastases of Melanoma
NCT03728465 ·Status: TERMINATED ·Phase: PHASE2
-
Immune Profiles Evolution Under Immunotherapy for Melanoma
NCT04576429 ·Status: RECRUITING ·Phase: NA
-
Nivolumab +/- Ipilimumab Immunomonitoring in Metastatic Melanoma
NCT03225365 ·Status: COMPLETED ·Phase: NA
-
A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors
NCT05585320 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma
NCT05732805 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study of the Activity of PD-1 Inhibitors in Metastatic Uveal Melanoma
NCT03964298 ·Status: COMPLETED
-
A Study to Test the Benefit of a New Anti-cancer Treatment in Patients With Unresectable Advanced Melanoma
NCT00942162 ·Status: COMPLETED ·Phase: PHASE2
-
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
NCT05317858 ·Status: RECRUITING ·Phase: PHASE3
-
Safety and Efficacy Study of QLF31907 in Advanced Melanoma and Urothelial Carcinoma
NCT05823246 ·Status: UNKNOWN ·Phase: PHASE2
-
An Open-Label, Dose-Escalation Study of IMC-20D7S In Participants With Malignant Melanoma
NCT01137006 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Study of BCD-145 (Anti-CTLA-4) in Patients With Unresectable/Metastatic Melanoma
NCT03472027 ·Status: COMPLETED ·Phase: PHASE1
-
Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma
NCT02073123 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Clinical Study, to Evaluate the Safety and Tolerability of Intradermal IMM-101 in Adult Melanoma Cancer Patients
NCT01308762 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Investigational Treatments in Combination With Standard of Care Immune Checkpoint Inhibitors in Participants With Advanced Melanoma
NCT02723006 ·Status: TERMINATED ·Phase: PHASE1
-
Safety and Efficacy Study of Pembrolizumab (MK-3475) in Chinese Participants With Locally Advanced or Metastatic Melanoma (MK-3475-151/KEYNOTE-151)
NCT02821000 ·Status: COMPLETED ·Phase: PHASE1
-
Understanding and Anticipating Therapeutic Response And Immuno-meDIated Adverse Events in Anti-cancer Immune-checkpoint Inhibition: a Tissue Biopsy Based imaGing Study
NCT05921123 ·Status: RECRUITING
-
Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy
NCT03290677 ·Status: COMPLETED ·Phase: NA
-
Exploratory Interventional Study of Prognostic Serum Biomarkers of Cancer Progression
NCT05426317 ·Status: UNKNOWN ·Phase: NA
-
Phase I Clinical Trial of Tremelimumab Plus MEDI3617 in Patients With Unresectable Stage III or Stage IV Melanoma
NCT02141542 ·Status: COMPLETED ·Phase: PHASE1
-
Immunotherapy and Carbon Ion Radiotherapy In Solid Cancers With Stable Disease
NCT05229614 ·Status: RECRUITING ·Phase: PHASE2