Clinical Status and Bronchial Inflammation in Patients With Bronchiolitis Obliterans
NCT01327248 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2012-06-27
Summary
The aim of this case-control study is the characterization of the bronchial and systemic inflammation of children and young adults with bronchiolitis obliterans.
On the first visit subjects are asked to perform a lung function test (spirometry, body plethysmography with helium). Further levels of eNO and eCO are determined. A blood sample is drawn to describe the inflammatory status. Bronchial inflammation will be measured in induced sputum. At the second visit, a non-specific bronchial provocation testing (PD20 FEV1 methacholine) is performed.
Conditions
- Bronchiolitis Obliterans
Sponsors & Collaborators
-
Johann Wolfgang Goethe University Hospital
lead OTHER
Principal Investigators
-
Martin Rosewich, MD · Goethe University
Eligibility
- Min Age
- 6 Years
- Max Age
- 25 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-05-31
- Primary Completion
- 2012-05-31
- Completion
- 2012-06-30
Countries
- Germany
Study Locations
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