Effect of Air Pollution in the Haifa Bay Area on Cardiovascular Morbidity and Mortality
NCT01325155 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 5000
Last updated 2011-03-29
Summary
The association between exposure to ambient air pollution and pulmonary disease has been well established.To date no study has assessed the burden of cardiovascular disease in Israel and its relation to ambient air pollution.
The Haifa Bay Area has a long history of industrialization including possessing the nation's largest oil refineries, oil-fired power plant, agrochemical and cement producers, industrial incinerators and the Eastern Mediterranean's busiest port. The presence of industrial and mobile sources, combined with a basin effect has contributed to air pollution in the Haifa Bay Area and has raised concerns about potential health effects.
Research Objectives
* Determine if the increased rate of cardiovascular mortality in Haifa is associated with PM 2.5 concentrations.
* Assess effect modification in diverse sub-populations.
* If an association does exist, assess the economic burden of PM 2.5 associated cardiovascular morbidity and mortality.
* Design prediction models of daily cardiovascular emergency department visits based on daily and seasonal variation of air pollution.
Conditions
- Acute Coronary Syndrome
- Heart Failure
- Arrhythmia
Sponsors & Collaborators
-
Rambam Health Care Campus
lead OTHER
Principal Investigators
-
Haim Hammerman, prof · Rambam Health Care Campus
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-04-30
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