Contrast Enhanced Harmonic Endoscopic Ultrasound (CEH-EUS) in Focal Pancreatic Masses

Summary

The aim of the study is to assess the accuracy of real-time perfusion imaging pattern of pancreatic focal lesions visualized by contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) for the differential diagnosis between chronic pseudotumoral pancreatitis and pancreatic cancer in a prospective multicenter design.

The study will include patients with focal pancreatic masses evaluated by CEH-EUS and EUS-FNA. The diagnosis is usually unknown in the moment of the initial evaluation, the patients being included based on a suspicion of focal pancreatic masses after transabdominal ultrasound, CT or MR examinations. However, after a complete evaluation, a final diagnosis will be reached based on the combination of EUS-FNA cytology/pathology, surgical pathology and minimum 12 months follow-up.

Conditions

• Adenocarcinoma Pancreas
• Chronic Pancreatitis

Sponsors & Collaborators

• Copenhagen University Hospital, Denmark

  collaborator OTHER

• Caritas-Krankenhaus Bad Mergentheim

  collaborator OTHER

• Institut Paoli-Calmettes

  collaborator OTHER

• University of Witten/Herdecke

  collaborator OTHER

• Hospital Meiningen Germany

  collaborator UNKNOWN

• Odense University Hospital

  collaborator OTHER

• University of Santiago de Compostela

  collaborator OTHER

• Università Vita-Salute San Raffaele

  collaborator OTHER

• SRH Wald-Klinikum Gera GmbH

  collaborator OTHER

• University of Bergen

  collaborator OTHER

• Institutul Clinic Fundeni

  collaborator OTHER

• Glasgow Royal Infirmary

  collaborator OTHER

• University College, London

  collaborator OTHER

• University of Medicine and Pharmacy Craiova

  lead OTHER

Principal Investigators

• Adrian Săftoiu, Professor · University of Medicine and Pharmacy Craiova, Romania

Eligibility

Min Age

18 Years

Max Age

90 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-03-31

Primary Completion

2012-04-30

Completion

2012-12-31

Countries

• Denmark
• France
• Germany
• Italy
• Norway
• Romania
• Spain
• United Kingdom

Study Locations