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Circadian Sleep-wake Cycles and Light Therapy in Borderline Personality Disorder

NCT01311193 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL

Last updated 2011-03-09

No results posted yet for this study

Summary

Individuals with borderline personality disorder (BPD) frequently suffer from emotional instability, daytime fatigue and sleep disturbances. The investigators examined circadian rhythms, sleep and well-being in women with BPD under their habitual life conditions with and without light treatment.

Treated women diagnosed with BPD were investigated during 3 weeks without and 3 weeks with morning LT. Rest-activity cycles were continuously measured using wrist actigraphy, together with proximal skin temperature. Saliva samples were collected weekly to determine the diurnal melatonin rhythm. A range of self-ratings and questionnaires were used to assess depression and clinical state throughout the 6-week protocol. Ten matched healthy women followed the same 6-week protocol without light treatment.

Conditions

Interventions

OTHER

light therapy

early morning exposures to bright light, 8000lux for 40min, daily during 3 weeks

Sponsors & Collaborators

  • Velux Fonden

    collaborator OTHER

  • Lumie UK

    collaborator UNKNOWN

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Christian Cajochen, PhD · Centre for Chronobiology, Psychiatric Hospital, University of Basel

Eligibility

Min Age
20 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01311193 on ClinicalTrials.gov