Evaluation of Neuroprotective Effect of Minocycline
NCT01297816 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2011-02-17
Summary
This process appears as a incredible and progressive event that will not stop till reattachment of RPE and neurosensory retina happened .
Process of degeneration begins from first hours of RD (Retinal Detachment) establishment Neuroprotection of photoreceptor following RD is a novel and debatable discussion encountered in recent years .
How to stop this phenomena and neuroprotective agent role in this issue are a new interest of researcher.
In the study the investigators are planning to perform a clinical trial to demonstrate the minocycline neuroprotective effect in a double blind design as this impact has been implicated previously in a animal study
Conditions
- Retinal Detachment
Interventions
- DRUG
-
100mg,BD, fo three month
- DRUG
-
Minocycline
100mg
Sponsors & Collaborators
-
Shahid Beheshti University of Medical Sciences
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 8 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-12-31
- Primary Completion
- 2010-12-31
- Completion
- 2011-04-30
Countries
- Iran
Study Locations
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