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Mechanisms of Infertility and Hormonal Changes in Patients With Chronic Kidney Disease

NCT01294904 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2018-12-21

No results posted yet for this study

Summary

Patients with chronic kidney disease (both men and women), especially those with terminal renal failure, manifest infertility. There has been demonstrated several hormonal changes in patients on dialysis. Increased levels of luteinizing hormone (LH) has been seen in men (12). In women the opposite has been reported. The number of spermatocytes is reduced and a disturbance in maturation has been observed.

This project is aimed to study the influence of uremic milieu on fertility in men and women. The hypopituitary/hypothalamus gland axis and hormonal levels will be studied.

Conditions

Sponsors & Collaborators

  • Lund University

    lead OTHER

Principal Investigators

  • Anders Christensson, MD · Lund University

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-01-31
Primary Completion
2017-05-31
Completion
2018-08-31

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01294904 on ClinicalTrials.gov