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The Bupivacaine Dose Sparing Effect of Intrathecal Epinephrine

NCT01261078 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2011-07-20

No results posted yet for this study

Summary

Intrathecal epinephrine has been known to increase the duration of spinal anesthesia, or increase the quality of anesthesia. However, there is still a controversy, and the mechanism of epinephrine is recently suggested as a modulator of pain information in the spinal cord. Therefore, the investigators try to investigate the dose sparing effect of intrathecal epinephrine for spinal anesthesia with bupivacaine.

Conditions

  • Spinal Anesthesia

Interventions

DRUG

Placebo

intrathecal 8 mg of bupivacaine only

DRUG

epinephrine 25

intrathecal 8 mg of bupivacaine mixed with 25 mcg of epinephrine

DRUG

Epinephrine 50

intrathecal 8 mg of bupivacaine mixed with 50 mcg of epinephrine

DRUG

epinephrine 100

intrathecal 8 mg of bupivacaine mixed with 0.1 mg of epinephrine

DRUG

Epi 200

intrathecal bupivacaine 8 mg with 200 mcg of epinephrine

Sponsors & Collaborators

  • Seoul Medical Center

    lead OTHER

Principal Investigators

  • Won Ho Kim, M.D. · Seoul Medical Center

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-12-31
Primary Completion
2011-07-31
Completion
2011-07-31

Countries

  • South Korea

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01261078 on ClinicalTrials.gov