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Pilot Study of How Children With Asthma Exacerbations Metabolize Prednisone

NCT01260623 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2017-08-28

No results posted yet for this study

Summary

The objective of the investigators pilot study is to assess the pharmacokinetic profile of two corticosteroid drugs, prednisone and prednisolone, in children who present to the pediatric emergency department with an asthma exacerbation. The investigators hypothesis is that the pharmacokinetic profile in this population will be similar to healthy children and adults.

Conditions

  • Asthma Exacerbation

Interventions

DRUG

Prednisolone and prednisone

oral, or intravenous prednisone, prednisolone, given the first time for asthma exacerbation

Sponsors & Collaborators

  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    lead OTHER

Principal Investigators

  • Michael Rieder, MD, Ph.D, FRCPC · Pediatric Emergency Dept, Children's Hospital, London Health Sciences Centre

Eligibility

Min Age
2 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-09
Primary Completion
2013-05-31
Completion
2013-05-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01260623 on ClinicalTrials.gov