PhII Study STA-9090 as Second or Third-Line Therapy for Metastatic Pancreas Cancer
NCT01227018 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2014-07-23
Summary
RATIONALE: Heat shock protein (HSP)90 inhibitor STA-9090 may stop the growth of tumor cells by blocking some of the proteins needed for cell growth. PURPOSE: This phase II trial is studying how well hsp90 inhibitor STA-9090 works as second- or third-line therapy for the treatment of patients with metastatic pancreatic cancer.
Conditions
- Adenocarcinoma of the Pancreas
- Recurrent Pancreatic Cancer
- Stage IV Pancreatic Cancer
Interventions
- DRUG
-
STA-9090
Given IV
- RADIATION
-
Radiologic imaging
radiologic modalities used to evaluate response to treatment
- PROCEDURE
-
blood draw
Venous blood will be drawn from those patients who give consent. Serum will be used to look for biomarkers predictive of response
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Vanderbilt-Ingram Cancer Center
lead OTHER
Principal Investigators
-
Dana Cardin, MD · Vanderbilt-Ingram Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-12-31
- Primary Completion
- 2013-05-31
- Completion
- 2013-05-31
Countries
- United States
Study Locations
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