Perifosine in Treating Patients With Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer
NCT00059982 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-24
Summary
RATIONALE: Perifosine may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth.
PURPOSE: Phase II trial to study the effectiveness of perifosine in treating patients who have locally advanced, unresectable, or metastatic pancreatic cancer.
Conditions
Interventions
- DRUG
-
perifosine
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Eastern Cooperative Oncology Group
lead NETWORK
Principal Investigators
-
Robert de W. Marsh, MD · University of Florida
-
Caio Max S. Rocha Lima, MD · H. Lee Moffitt Cancer Center and Research Institute
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-07-31
- Completion
- 2005-08-31
Countries
- United States
Study Locations
More Related Trials
-
PhII Study STA-9090 as Second or Third-Line Therapy for Metastatic Pancreas Cancer
NCT01227018 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy of PERT for PEI in Unresectable Pancreatic Cancer.
NCT06099119 ·Status: RECRUITING ·Phase: PHASE4
-
Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer
NCT01232829 ·Status: COMPLETED ·Phase: PHASE2
-
Niraparib in Metastatic Pancreatic Cancer After Previous Chemotherapy (NIRA-PANC): a Phase 2 Trial
NCT03553004 ·Status: UNKNOWN ·Phase: PHASE2
-
R115777 in Treating Patients Who Have Metastatic Pancreatic Cancer
NCT00005843 ·Status: COMPLETED ·Phase: PHASE2
-
RO4929097 Before Surgery in Treating Patients With Pancreatic Cancer
NCT01192763 ·Status: TERMINATED ·Phase: PHASE1
-
Adjuvant Chemoradiotherapy and Interferon Alfa in Treating Patients With Resected Pancreatic Cancer
NCT00059826 ·Status: COMPLETED ·Phase: PHASE2
-
Vitamin E δ-Tocotrienol Administered to Subjects With Resectable Pancreatic Exocrine Neoplasia
NCT00985777 ·Status: COMPLETED ·Phase: PHASE1
-
TAS-102 (Lonsurf) in Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma Post First Line Chemotherapy (UF-STO-PANC-003)
NCT02921737 ·Status: TERMINATED ·Phase: PHASE2
-
Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer
NCT02575508 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery
NCT01954732 ·Status: WITHDRAWN ·Phase: PHASE1
-
Fluorouracil With or Without Cisplatin in Treating Patients With Advanced or Metastatic Cancer of the Pancreas
NCT00003029 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer
NCT05766748 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
NCT04172532 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
CPI-613 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
NCT01839981 ·Status: COMPLETED ·Phase: PHASE1
-
Opioid Growth Factor in Treating Patients With Advanced Pancreatic Cancer That Cannot Be Removed By Surgery
NCT00109941 ·Status: COMPLETED ·Phase: PHASE2
-
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
NCT06998940 ·Status: RECRUITING ·Phase: PHASE3
-
Clinical Study Evaluating the Effect of Losartan
NCT06539806 ·Status: RECRUITING ·Phase: NA
-
Phase 2 Study of S-1 as 2nd Line Therapy in Metastatic Pancreatic Cancer
NCT00652054 ·Status: COMPLETED ·Phase: PHASE2
-
Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma
NCT07214298 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer
NCT03300921 ·Status: TERMINATED ·Phase: PHASE1
-
ISIS 2503 in Treating Patients With Advanced Cancer of the Pancreas
NCT00005594 ·Status: COMPLETED ·Phase: PHASE2
-
Saracatinib in Treating Patients With Previously Treated Metastatic Pancreatic Cancer
NCT00735917 ·Status: COMPLETED ·Phase: PHASE2
-
Capecitabine and Oxaliplatin in Patients With Advanced or Metastatic Pancreatic Adenocarcinoma
NCT00585078 ·Status: COMPLETED ·Phase: PHASE2
-
Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors
NCT02495896 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1