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Hemolysis in Patients With Hereditary Spherocytosis (HS)

NCT01201174 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2010-09-14

No results posted yet for this study

Summary

In the present study the investigators are going to explore the oxidative status of HS-RBC and its contribution to hemolysis

Conditions

  • Hereditary
  • Hemolysis

Interventions

OTHER

fermented papaya preparation (FPP)

Hemolysis will be assayed by suspending 3 ml of packed RBC in PBS or in the autologous plasma and overnight incubation in the presence of various concentrations of antioxidants such as fermented papaya preparation (FPP) at 37oC in humidified atmosphere of 5% CO2 in air (10). Following 5 min centrifugation at 800 rpm, the supernatants will collected for Hb determination by measuring the absorbance at 540 nm.

Sponsors & Collaborators

  • Wolfson Medical Center

    lead OTHER_GOV

Principal Investigators

  • GHOTI HOSSAM, doctor · HEMATOLOGY DEPARTMENT ON WOLFSSON MEDICAL CENTER

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
5 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-09-30
Primary Completion
2011-09-30
Completion
2011-09-30

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01201174 on ClinicalTrials.gov