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Lifestyle Modifications and the Progression of Chronic Kidney Disease

NCT01179906 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2010-08-11

No results posted yet for this study

Summary

Aerobic training has been shown to favorably alter several of the known risk factors for coronary artery disease including hypertension, dyslipidemia, obesity, and diabetes (1). It seems logical that if these risk factors were aggressively controlled in patients with chronic kidney disease (CKD) by implementing lifestyle changes (e.g., diet and exercise training) to support the pharmacologic interventions that are necessary for the control of the disease, then the rate of progression of the disease may be altered. However, to date, there is no clear research evidence to support this hypothesis. Therefore the aims of the proposed study are:

1. To test the hypothesis that lifestyle interventions (i.e., dietary modification and regular, long-term aerobic exercise training) will favorably alter the natural progression of CKD in a sample of patients compared to a control group who will receive the current standard care.
2. To explore possible mechanisms that could contribute to the observed changes.

Conditions

  • Patients With Stage 2-4 Chronic Kidney Disease

Interventions

BEHAVIORAL

Exercise training

Subjects exercise trained for 48 weeks with personal trainers at a college wellness center

BEHAVIORAL

Diet modification

Exercise training using personal trainers 3 times per week. Individuals were trained at a moderate intensity

Sponsors & Collaborators

  • Western New England Renal & Transplant Associates

    collaborator UNKNOWN

  • Springfield College

    lead OTHER

Principal Investigators

  • Sam A Headley, Ph.D · Springfield College

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2009-02-28
Completion
2009-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01179906 on ClinicalTrials.gov